Mesterolone: Proviron

One of the biggest advantages associated with use of Proviron is its unique ability to promote the count and quality of sperm and is also indicated to treat serious wellness problems such as low libido and erectile malfunction. The drug is even recommended to male patients struggling with impotency or lack of testosterone.

In addition to these advantages, use of Mesterolone is also associated with improved release of luteinizing hormone and follicle-stimulating hormone for stimulating testes so that more testosterone can be produced.

Since it is not a 17 alpha alkylated compound, it can be used for a long period of time. The drug can even enhance potency of testosterone when used in an anabolic steroid cycle with it. The fact that Proviron can attach itself to SHBG (sex hormone-binding globulin) and albumin means that a large percentage of testosterone (free) is made available to conduct anabolic actions.

Furthermore, the performance enhancing drug can also be used as an anti-aromatase and this characteristic proves to be beneficial when the drug is stacked with other anabolic steroids and performance enhancing drugs that may convert to estrogen to some extent. Since this steroid can bind to the aromatase enzyme, it does not allow steroids that are made a part of the cycle (with Proviron) to interact with enzymes and lead to formation of estrogens.

The drug has an anabolic-androgenic ratio of 100-150: and can be detected over a period of 5-6 weeks.

Dosages range between 25-50mg daily.

Increased sexual libido, hardened musculature, water loss, and enhanced erections are side effects of mesterlone.

Combined with Viagra and/or Cialis is very popular in bodybuilding industry.


Great study on treating depression with proviron.

Database: PsycINFO
[ Journal Article ]
A comparison of the antidepressant effects of a synthetic androgen (mesterolone) and amitriptyline in depressed men.
Vogel, William; Klaiber, Edward L.; Broverman, Donald M.
Journal of Clinical Psychiatry, Vol 46(1), Jan 1985, 6-8.


26 depressed male outpatients were randomly assigned to 14 weeks of treatment with either mesterolone or amitriptyline in a double-blind parallel treatment design. Ss completed the Hamilton Rating Scale for Depression and a symptom checklist each week. Findings reveal that the drugs were equally effective in reducing depressive symptoms. Mesterolone produced significantly fewer adverse side effects than amitriptyline and did not produce hypomania or tachycardia, recognized side effects of amitriptyline.

(PsycINFO Database Record (c) 2013 APA, all rights reserved)
Methods Find Exp Clin Pharmacol. 1984 Jun;6(6):331-7.
The effects of mesterolone, a male sex hormone in depressed patients (a double blind controlled study).
Itil TM, Michael ST, Shapiro DM, Itil KZ.

Based on computer EEG (CEEG) profiles, in high doses, antidepressant properties of mesterolone, a synthetic androgen, were predicted. In a double-blind placebo controlled study, the clinical effects of 300-450 mg daily mesterolone were investigated in 52 relatively young (age range 26-53 years, mean 42.7 years) male depressed outpatients. During 6 weeks of mesterolone treatment, there was a significant improvement of depressive symptomatology. However, since an improvement was also established during the placebo treatment, no statistically appreciable difference in the therapeutic effects of mesterolone was established compared to placebo. Mesterolone treatment significantly decreased both plasma testosterone and protein bound testosterone levels. Patients with high testosterone levels prior to treatment seem to have had more benefit from mesterolone treatment than patients with low testosterone levels. The degree of improvement weakly correlated to the decrease of testosterone levels during mesterolone treatment.


Great article XXL. You know I love me some Proviron.


I can easily say it’s my top favorite oral, well besides 69 & a BJ :wink:


I agree, i use it with everything. Love it. It’s hard to pinpoint why, but after I started using it, just feel overall better. Physically & mentally

Well played my friend… well played…

Superb info and true all around @XXL

Ever try crushing up the pill and letting it dissolve under the tongue to absorb? Little sippy sip of everclear acts as a solvent :ok_hand:

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Does whiskey work the same?

Yessir but the only problem with whiskey is that…it tastes too damn good u might not be able to stop at a sip

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Shit! You are right. Damn it! That does go well with orals. But it does go well with oral. It’s amazing how one letter can really change the meaning of a word.